Anti-POLR2E (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P19388
Gene Id	5434
Gene Symbols	POLR2E
Protein Name / Synonyms	POLR2E (N-term)
Clonality	Polyclonal
Preparation	This POLR2E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human POLR2E.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1; DNA-directed RNA polymerase II 23 kDa polypeptide; DNA-directed RNA polymerase II subunit E; RPB5 homolog; XAP4

NCBI Accession #

NP_002686.2

Other Accession #

B0BNE2; Q80UW8; NP_002686.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

24551

Recommended Dilutions

WB: 1:1000

POLR2E Antibody (N-term) (Cat# 102-12478) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the POLR2E antibody detected the POLR2E protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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