RayBiotech

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ISO 13485:2016 cGMP

Anti-PPAN Antibody

Catalog #: 144-66376

PPAN pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse
Host SpeciesRabbit
Accession Number
Q9NQ55
Gene Id
56342
Gene Symbols
PPAN
Protein Name / Synonyms
PPAN, BXDC3, SSF, SSF-1, SSF1, SSF2, suppressor of SWI4 1 homolog
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting, IHC, IF
Shipping TypeBlue ice
Storage-20°C

Description

Background

The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.

Dilutions

WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200

Format

Calculated MW
51kDa/53kDa/58kDa
Observed MW
53kDa/55kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PPAN (NP_064615.3).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.