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Anti-PPP2R4 Antibody
Catalog #: 144-65411
PPP2R4 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q15257 |
| Gene Id | 5524 |
| Gene Symbols | PPP2R4 |
| Protein Name / Synonyms | PTPA, PP2A, PPP2R4, PR53, protein phosphatase 2 phosphatase activator |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | IHC, IF |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Dilutions
IHC 1:50 - 1:200; IF 1:50 - 1:200
Format
Calculated MW
31kDa/33kDa/36kDa/40kDa
Observed MW
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human PPP2R4 (NP_821067.1).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.