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Anti-PRKAG3 (C-term) Antibody
Catalog #: 102-13181
Rabbit Anti-Human PRKAG3 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9UGI9 |
| Gene Id | 53632 |
| Gene Symbols | PRKAG3 |
| Protein Name / Synonyms | PRKAG3 (C-term) |
| Clonality | Polyclonal |
| Preparation | This PRKAG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-454 amino acids from the C-terminal region of human PRKAG3. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq].
Specificity
Predicted Reactivity
Mouse, Bovine
Other Names
PRKAG3; AMPKG3; 5'-AMP-activated protein kinase subunit gamma-3
NCBI Accession #
NP_059127.2
Other Accession #
Q8BGM7; Q2LL38; NP_059127.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
54258
Recommended Dilutions
WB: 1:1000
 | PRKAG3 Antibody (C-term) (Cat# 102-13181) western blot analysis in Hela,HepG2,RD cell line lysates (35ug/lane).This demonstrates the PRKAG3 antibody detected the PRKAG3 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.