Anti-Profilin-1 Antibody

Product Description

Specifications

Size	200 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	P07737\|P62963\|P02584\|P62962
Gene Id	5216
Gene Symbols	PFN1
Protein Name / Synonyms	Profilin-1, Epididymis tissue protein Li 184a, Profilin I, PFN1
Clonality	Polyclonal
Clone	RB55919
Isotype	Kappa, Rabbit
Recommended Applications	FC, Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

Other Information

Antigen Type

Synthesized Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

15054

Antigen Source

Human

Images

FC (1:25)

Overlay histogram showing Hela cells stained with 102-25109 (green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (102-25109, 1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed(OH191631) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG (1?g/1x10

Expiration:

12 months from the date of shipment when stored properly.

Featured Products