Anti-PSEN2 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P49810
Gene Id	5664
Gene Symbols	PSEN2
Protein Name / Synonyms	PSEN2 (N-term)
Clonality	Polyclonal
Preparation	This PSEN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-65 amino acids from the N-terminal region of human PSEN2(Presenilin-2 NTF subunit).
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, FC
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.

Specificity

Other Names

Presenilin-2, PS-2, 3423-, AD3LP, AD5, E5-1, STM-2, Presenilin-2 NTF subunit, Presenilin-2 CTF subunit, PSEN2, AD4, PS2, PSNL2, STM2

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

50140

Recommended Dilutions

WB: 1:1000

Western blot analysis of lysate from Hela cell line, using PSEN2(Presenilin-2 NTF subunit) Antibody (N-term)(Cat# 102-14953). 102-14953 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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