3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-PSMA5 (Center) Antibody
Catalog #: 102-12513
Rabbit Anti-Human PSMA5 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P28066 |
| Gene Id | 5686 |
| Gene Symbols | PSMA5 |
| Protein Name / Synonyms | PSMA5 (Center) |
| Clonality | Polyclonal |
| Preparation | This PSMA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the Central region of human PSMA5. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PMA5 is a member of the peptidase T1A family, that is a 20S core alpha subunit.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine
Other Names
PSMA5; Proteasome subunit alpha type-5; Macropain zeta chain; Multicatalytic endopeptidase complex zeta chain; Proteasome zeta chain
NCBI Accession #
NP_001186701.1;NP_001186702.1;NP_001186703.1;NP_002781.2
Other Accession #
P34064; Q9Z2U1; Q5E987
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
26411
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of PSMA5 (arrow) using rabbit polyclonal PSMA5 Antibody (Center) (Cat# 102-12513). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PSMA5 gene (Lane 2) (Origene Technologies). |
 | Western blot analysis of PSMA5 Antibody (Center) (Cat# 102-12513) in HL60 cell line lysates (35ug/lane). PSMA5(arrow) was detected using the purified polyclonal antibody. |
 | Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PSMA5 antibody (Center) (Cat# 102-12513), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.