Anti-PSTPIP1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O43586
Gene Id	9051
Gene Symbols	PSTPIP1
Protein Name / Synonyms	PSTPIP1 (N-term)
Clonality	Polyclonal
Preparation	This PSTPIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human PSTPIP1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, FC
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.

Specificity

Predicted Reactivity

Mouse

Other Names

PSTPIP1; CD2BP1; Proline-serine-threonine phosphatase-interacting protein 1; CD2-binding protein 1; H-PIP

NCBI Accession #

NP_003969.2

Other Accession #

P97814; NP_003969.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

47591

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	PSTPIP1 Antibody (N-term) (Cat# 102-11598) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PSTPIP1 antibody detected the PSTPIP1 protein (arrow).
	PSTPIP1 Antibody (N-term) (Cat# 102-11598) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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