Anti-PTGDS Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	P41222
Gene Id	5730
Gene Symbols	PTGDS
Protein Name / Synonyms	PTGDS, L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2, prostaglandin D2 synthase
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IHC
Shipping Type	Blue ice
Storage	-20°C

Description

Background

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

Dilutions

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Format

Calculated MW

21kDa

Observed MW

33kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 23-190 of human PTGDS (NP_000945.3).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of mouse heart, using PTGDS antibody (144-01889) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Western blot - PTGDS antibody (144-01889)

Immunohistochemistry of paraffin-embedded rat brain using PTGDS antibody (144-01889) at dilution of 1:200 (40x lens).
Immunohistochemistry - PTGDS antibody (144-01889)

Expiration:

12 months from the date of shipment when stored properly.

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