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Anti-PTH-RP Antibody
Catalog #: 130-10011
Rabbit anti-PTH-RP Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Accession Number | P12272 |
| Gene Id | 5744 |
| Gene Symbols | PTHLH PTHRP |
| Protein Name / Synonyms | Parathyroid hormone-related protein (PTH-rP) (PTHrP) (Parathyroid hormone-like protein) (PLP) [Cleaved into: PTHrP[1-36], PTHrP[38-94], Osteostatin (PTHrP[107-139])] |
| Immunogen | This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen (PTH-RP:CAVSEHQLLHDKGKSIQDLR). This antibody was produced from a rabbit immunized with this peptide conjugated with KLH. The IgG fraction was purified by Protein A affinity chromatography. |
| Immunogen Sequence | CAVSEHQLLHDKGKSIQDLR |
| Concentration (lot specific) | 1 mg/ml |
| Recommended Applications | ELISA (recommended work dilution= 1:10, 000) |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Description
Parathyroid hormone-related protein (or PTH-RP) is a protein member of the parathyroid hormone family. It is occasionally secreted by cancer cells (breast cancer, certain types of lung cancer includingsquamous cell lung carcinoma). However, it also has normal functions.PTHrP acts as an endocrine, autocrine, paracrine, and intracrine hormone. It regulates endochondral bone development by maintaining the endochondral growth plate at a constant width. It also regulates epithelial-mesenchymal interactions during the formation of the mammary glands.Diseases associated with PTHLH include Brachydactyly, Type E2 and Brachydactyly, Type E. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors.
Storage
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Expiration:
12 months from the date of shipment when stored properly.