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Anti-PTH-RP Antibody, Biotinylated
Catalog #: 130-10011B-50
Rabbit anti-PTH-RP Biotinylated Antibody, 50 ug
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P12272 |
| Gene Id | 5744 |
| Gene Symbols | PTHLH PTHRP |
| Protein Name / Synonyms | Parathyroid hormone-related protein (PTH-rP) (PTHrP) (Parathyroid hormone-like protein) (PLP) [Cleaved into: PTHrP[1-36], PTHrP[38-94], Osteostatin (PTHrP[107-139])] |
| Clonality | Polyclonal |
| Immunogen | This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen (PTH-RP:CAVSEHQLLHDKGKSIQDLR). This antibody was produced from a rabbit immunized with this peptide conjugated with KLH. The IgG fraction was purified by Protein A affinity chromatography. |
| Immunogen Sequence | CAVSEHQLLHDKGKSIQDLR |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1:10, 000) |
| Reconstitution | A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e.g. sodium azide). The final amount is indicated on the shipping vial. |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Parathyroid hormone-related protein (or PTH-RP) is a protein member of the parathyroid hormone family. It is occasionally secreted by cancer cells (breast cancer, certain types of lung cancer includingsquamous cell lung carcinoma). However, it also has normal functions.PTHrP acts as an endocrine, autocrine, paracrine, and intracrine hormone. It regulates endochondral bone development by maintaining the endochondral growth plate at a constant width. It also regulates epithelial-mesenchymal interactions during the formation of the mammary glands.Diseases associated with PTHLH include Brachydactyly, Type E2 and Brachydactyly, Type E. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors.
Storage
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Expiration:
12 months from the date of shipment when stored properly.