Rabbit Anti-PTPN5 (N-term) Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P54829|NP_001035059.1|NP_008837.1 |
| Gene Id | 84867 |
| Gene Symbols | PTPN5 |
| Protein Name / Synonyms | Tyrosine-protein phosphatase non-receptor type 5, Neural-specific protein-tyrosine phosphatase, Striatum-enriched protein-tyrosine phosphatase, STEP, PTPN5 |
| Clonality | Polyclonal |
| Clone | RB36818 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
STEP (Protein-tyrosine phosphatase striatum-enriched) is a neural-specific protein-tyrosine phosphatase. It is also known as PTPN5 (tyrosine-protein phosphatase, non-receptor type 5). STEP immunoreactive areas are most intense in the regions of the CNS receiving a dopaminergic input (e.g. striatum, basal ganglia). STEP is part of the NMDA receptor (R) complex and inhibits NMDAR single-channel activity and NMDAR-mediated synaptic current. Phosphorylation of STEP, via D1 and PKA activation by dopamine, decreases the activity of STEP by reducing its affinity for substrate.
Other Information
NCBI Accession #
NP_001035059.1;NP_001265165.1;NP_001265167.1;NP_001265168.1;NP_008837.1;NP_116170.3
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
63538
Antigen Source
Human
Images
WB (1:1000)
PTPN5 Antibody (N-term) (Cat. #102-22552) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PTPN5 antibody detected the PTPN5 protein (arrow).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.