Anti-PURB (C-term) Antibody

Product Description

Specifications

Size	200 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Mouse
Accession Number	Q96QR8
Gene Id	5814
Gene Symbols	PURB
Protein Name / Synonyms	Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB
Clonality	Monoclonal
Clone	2117CT1176.48.6
Isotype	Kappa, IgG1
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Has capacity to bind repeated elements in single- stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine- rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity).

Other Information

Antigen Type

Recombinant Protein

Format

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Calculated Molecular Weight (Da)

33241

Antigen Source

Human

Images

WB (1:8000)

All lanes : Anti-PURB Antibody (C-term) at 1:8000 dilution Lane 1: Jurkat whole cell lysate Lane 2: HeLa whole cell lysate Lane 3: NCI-H460 whole cell lysate Lane 4: HepG2 whole cell lysate Lane 5: MCF-7 whole cell lysate Lane 6: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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