Anti-QTRTD1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9H974
Gene Id	79691
Gene Symbols	QTRTD1
Protein Name / Synonyms	QTRTD1 (C-term)
Clonality	Polyclonal
Preparation	This QTRTD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-350 amino acids from the C-terminal region of human QTRTD1.
Concentration (lot specific)	0.250 mg/ml
Recommended Applications	Western Blotting, IHC-P, IF, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity).

Specificity

Other Names

QTRTD1; Queuine tRNA-ribosyltransferase subunit QTRTD1; Queuine tRNA-ribosyltransferase domain-containing protein 1

NCBI Accession #

NP_001243764.1;NP_001243765.1;NP_001243766.1;NP_078914.1

Other Accession #

NP_078914.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

46713

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50; IF: 1:10-50; FC: 1:10-50

	QTRTD1 Antibody (C-term) (Cat# 102-11212) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the QTRTD1 antibody detected the QTRTD1 protein (arrow).
	QTRTD1 Antibody (C-term) (Cat# 102-11212)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of QTRTD1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	Confocal immunofluorescent analysis of QTRTD1 Antibody (C-term)(Cat# 102-11212) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
	QTRTD1 Antibody (C-term) (Cat# 102-11212) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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