RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-RARA (C-term) Antibody

Catalog #: 102-12192

Rabbit Anti-RARA (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse
Host SpeciesRabbit
Accession Number
P10276
Gene Id
5914
Gene Symbols
RARA
Protein Name / Synonyms
RARA (C-term)
ClonalityPolyclonal
PreparationThis RARA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-349 amino acids from the C-terminal region of human RARA.
Concentration (lot specific)
0.340 mg/ml
Recommended ApplicationsWestern Blotting, IF, IHC-P, FC
Research AreaCancer
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.

Specificity

Other Names
RARA; NR1B1; Retinoic acid receptor alpha; Nuclear receptor subfamily 1 group B member 1
NCBI Accession #
NP_000955.1;NP_001019980.1;NP_001138773.1;NP_001138774.1
Other Accession #
NP_000955.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
50771
Recommended Dilutions
WB: 1:1000; IF: 1:10-50; IHC: 1:10-50; FC: 1:10-50
RARA Antibody (C-term) (Cat# 102-12192) western blot analysis in HL-60 cell line and mouse testis tissue lysates (35ug/lane).This demonstrates the RARA antibody detected the RARA protein (arrow).
Confocal immunofluorescent analysis of RARA Antibody (C-term) (Cat# 102-12192) with MCF-7 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
RARA Antibody (C-term) (Cat# 102-12192)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RARA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
RARA Antibody (C-term) (Cat# 102-12192) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.