Anti-RASA3 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q14644
Gene Id	22821
Gene Symbols	RASA3
Protein Name / Synonyms	RASA3 (C-term)
Clonality	Polyclonal
Preparation	This RASA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 594-623 amino acids from the C-terminal region of human RASA3.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.

Specificity

Other Names

RASA3; Ras GTPase-activating protein 3; GAP1(IP4BP); Ins P4-binding protein

NCBI Accession #

NP_031394.2

Other Accession #

NP_031394.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

95699

Recommended Dilutions

WB: 1:1000

RASA3 Antibody (C-term) (Cat# 102-14108) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the RASA3 antibody detected the RASA3 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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