Anti-RBBP7 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q16576
Gene Id	5931
Gene Symbols	RBBP7
Protein Name / Synonyms	RBBP7 (Center)
Clonality	Polyclonal
Preparation	This RBBP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of human RBBP7.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine, Monkey

Other Names

RBBP7; RBAP46; Histone-binding protein RBBP7; Histone acetyltransferase type B subunit 2; Nucleosome-remodeling factor subunit RBAP46; Retinoblastoma-binding protein 7; Retinoblastoma-binding protein p46

NCBI Accession #

NP_001185648.1;NP_002884.1

Other Accession #

Q71UF4; Q60973; Q4R304; Q3SWX8; NP_002884.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

47820

Recommended Dilutions

WB: 1:1000

	RBBP7 Antibody (Center) (Cat# 102-12940) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RBBP7 antibody detected the RBBP7 protein (arrow).
	Western blot analysis of RBBP7 (arrow) using rabbit polyclonal RBBP7 Antibody (Center) (Cat# 102-12940). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RBBP7 gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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