Anti-RBBP8 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q99708
Gene Id	5932
Gene Symbols	RBBP8
Protein Name / Synonyms	RBBP8 (C-term)
Clonality	Polyclonal
Preparation	This RBBP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 763-792 amino acids from the C-terminal region of human RBBP8.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.

Specificity

Other Names

RBBP8; CTIP; DNA endonuclease RBBP8; CtBP-interacting protein; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; Sporulation in the absence of SPO11 protein 2 homolog

NCBI Accession #

NP_002885.1;NP_976036.1;NP_976037.1

Other Accession #

NP_976037.1; NP_976036.1; NP_002885.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

101942

Recommended Dilutions

WB: 1:1000

RBBP8 Antibody (C-term) (Cat# 102-12266) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RBBP8 antibody detected the RBBP8 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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