Anti-RGL4 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q8IZJ4\|NP_705843.1
Gene Id	266747
Gene Symbols	RGL4
Protein Name / Synonyms	Ral-GDS-related protein, hRGR, Ral guanine nucleotide dissociation stimulator-like 4, RalGDS-like 4, RGL4, RGR
Clonality	Polyclonal
Clone	RB37616
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL4 (ral guanine nucleotide dissociation stimulator-like 4), also known as Rgr, is a 473 amino acid protein that localizes to the cytoplasmic vesicle of cells. Belonging to the GEF family of proteins, RGL4 induces phosphorylation of ERKs, p38 and JNK kinases, and it increases the levels of GTP bound forms of Ral and Ras. Ras activation is crucial for the transforming activity of RGL4. Due to its similarity to Ral GDS, RGL4 may be implicated in carcinogenesis.

Other Information

NCBI Accession #

NP_705843.1

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

52346

Antigen Source

Human

Images

WB (1:1000)

RGL4 Antibody (N-term) (Cat. #102-22826) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the RGL4 antibody detected the RGL4 protein (arrow).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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