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Anti-RLN2 Antibody

Catalog #: 144-66257

RLN2 pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Rat
Host SpeciesRabbit
Accession Number
P04090
Gene Id
6019
Gene Symbols
RLN2
Protein Name / Synonyms
RLN2, H2, H2-RLX, RLXH2, bA12D24.1.1, bA12D24.1.2, relaxin 2
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting, IHC
Research AreaAngiogenesis
Shipping TypeBlue ice
Storage-20°C

Description

Background

This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects.

Dilutions

WB 1:500 - 1:2000; IHC 1:50 - 1:200

Format

Calculated MW
12kDa/21kDa
Observed MW
21kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 25-185 of human RLN2 (NP_604390.1).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.