Anti-RNF128 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q8TEB7
Gene Id	79589
Gene Symbols	RNF128
Protein Name / Synonyms	RNF128 (Center)
Clonality	Polyclonal
Preparation	This RNF128 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the Central region of human RNF128.
Concentration (lot specific)	0.290 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specificity

Predicted Reactivity

Bovine

Other Names

RNF128; GRAIL; E3 ubiquitin-protein ligase RNF128; Gene related to anergy in lymphocytes protein; RING finger protein 128

NCBI Accession #

NP_078815.3;NP_919445.1

Other Accession #

Q29RU0; NP_078815.3

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

46521

Recommended Dilutions

WB: 1:1000

RNF128 Antibody (Center)(Cat# 102-14249) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the RNF128 antibody detected the RNF128 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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