Anti-RNF34 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q969K3
Gene Id	80196
Gene Symbols	RNF34
Protein Name / Synonyms	RNF34 (C-term)
Clonality	Polyclonal
Preparation	This RNF34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human RNF34.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine

Other Names

RNF34; E3 ubiquitin-protein ligase RNF34; Caspase regulator CARP1; Caspases-8 and -10-associated RING finger protein 1; FYVE-RING finger protein Momo; Human RING finger homologous to inhibitor of apoptosis protein; RING finger protein 34; RING finger protein RIFF

NCBI Accession #

NP_001243787.1;NP_079402.2;NP_919247.1

Other Accession #

Q6AYH3; Q99KR6; Q5E9J6; NP_079402.2; NP_919247.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

41641

Recommended Dilutions

WB: 1:1000

RNF34 Antibody (C-term) (Cat# 102-13069) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the RNF34 antibody detected the RNF34 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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