Anti-ROR2 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	Q01974
Gene Id	4920
Gene Symbols	ROR2
Protein Name / Synonyms	ROR2, BDB, BDB1, NTRKR2, receptor tyrosine kinase like orphan receptor 2
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Background

The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW

104kDa

Observed MW

145kDa

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ROR2 (NP_004551.2).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of U-87MG cells, using ROR2 antibody (144-05620) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Western blot - ROR2 antibody (144-05620)

Expiration:

12 months from the date of shipment when stored properly.

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