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Anti-S100A9 Antibody, Sodium Azide Free
Catalog #: 188-11386-SAF
Mouse anti-Human S100A9 Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Mouse |
| Accession Number | P06702 |
| Gene Id | 6280 |
| Gene Symbols | S100A9,CAGB,CFAG,MRP14 |
| Protein Name / Synonyms | Protein S100-A9 (Calgranulin-B) (Calprotectin L1H subunit) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9) |
| Immunogen | Recombinant human protein was used as the immunogen for the S100A9 antibody. |
| Isotype | Kappa, IgM |
| Purity | PEG precipitation |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | Immunofluorescence: 1-2ug/ml Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT (1) |
| Domain / Region / Terminus | Cytoplasmic, extracellular (secreted) and cell surface |
| Research Area | Inflammation, Autophagy |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
S100A9, also known as Calgranulin B or MRP14, is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. [UniProt]
Storage
Store the S100A9 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.