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Anti-S100P Antibody
Catalog #: 130-10036
Rabbit Anti-Human S100P Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Accession Number | P25815 |
| Gene Id | 6286 |
| Gene Symbols | S100P S100E |
| Clonality | Polyclonal |
| Immunogen | Immunogen was recombinant protein derived from Human S100P. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbitt serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography. |
| Recommended Applications | ELISA (recommended work dilution= 1: 80, 000(at least detecting 12.5ng/ml)) |
| Antigen Catalog Number | 230-00031 |
| Reconstitution | Supplied as lyophilized and purified antibody originally containing PBS, without Preservative Stabilizers, such as Sodium Azide. The final concentration is indicated on the shipping vial. The antibody is stable for at least years from the data of receipt when stored at -20°C to -70°C. Reconstituted antibody (recommended with H20 1 mg/ml) can also be aliquoted and stored frozen at -20°C to -70°C in a manual defrost freezer for months without detectable loss activity. Upon reconstitution, the antibody can also be stored over months at 4°C. Please avoid freeze-thaw cycles. |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
S100 calcium-binding protein P (S100P) is one member of S100 family and shares 50% sequence identity with human S100A1 and 44% identity with S100B. S100P contains 2 EF-hands (calcium binding domains) with different affinities for Ca2+, Zn2+ and Mg2+, a central hinge region and the Cterminal extension. S100P presents in various normal tissues (such as lung, placenta, kidney, heart, bladder, spleen, bone marrow, prostate gland, and intestinal mucosa), malignant tissues (such as non-small-cell lung cancer, melanoma, gastric adenocarcinoma, ovarian, breast, colon and prostate carcinoma), and the body fluids (such as blood, pancreatic juice, tear, and urine).
Specificity
The antibody can specifically bind to its immunogen, and did not show any cross reactivity with unrelated antigens in ELISA. The specificity for binding to recombinant protein, cellular protein and native antigen is not defined. Cross reactivity with mouse and rat S100P has not yet been tested.
Storage
Keep it at 4°C if intended for use within a month. Store at -20°C if over months. Minimize freezing and thawing when use.
Related Products
Recombinant Human S100P (cat#230-00031)Recombinant Human S100 Calcium Binding Protein P(cat#230-00031-3)
References
- Donato R. S100: a multigenic family of calciummodulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int J Biochem Cell Biol.2001. 33(7): 637-68.
- Basu GD, et al. Functional evidence implicating S100P in prostate cancer progression. Int J Cancer.2008. 15;123(2):330-9.
Expiration:
12 months from the date of shipment when stored properly.