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Anti-SAFB1 Antibody
Catalog #: 102-26490
Mouse Anti-SAFB1 Antibody, 100 µl
Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | Q15424 |
| Gene Id | 6294 |
| Gene Symbols | SAFB |
| Protein Name / Synonyms | DKFZp779C1727;glutathione S transferase fusion protein;HAP;HET;HSP27 ERE TATA binding protein;HSP27 ERE-TATA-binding protein;HSP27 estrogen response element-TATA box-binding protein;SAF B;SAF-B1;SAFB 1;SAFB;SAFB1;SAFB1_HUMAN;scaffold attachment factor B1. |
| Clonality | Monoclonal |
| Recommended Applications | Western Blotting, ICC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity). Can inhibit cell proliferation.
Other Information
Antigen Type
Recombinant Protein
Images
WB (1:1000)
Western blot detection of SAFB1 in HelaNE,A431,MDA-MB-468,Breast cancer,ZR75-1 and MCF7 cell lysates using SAFB1 mouse mAb (1:4000 diluted).Predicted band size: 130kDa.Observed band size: 130kDa.
ICC (1:200)
Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using SAFB1 mouse mAb (dilution 1:200).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.