Anti-SAP (Center E300) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P07602
Gene Id	5660
Gene Symbols	PSAP
Protein Name / Synonyms	SAP (Center E300)
Clonality	Polyclonal
Preparation	This SAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the Central region of human SAP.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.

Specificity

Other Names

PSAP; GLBA; SAP1; Proactivator polypeptide; Saposin-A; Protein A; Saposin-B-Val; Saposin-B; Cerebroside sulfate activator; Dispersin; Sphingolipid activator protein 1; Sulfatide/GM1 activator; Saposin-C; A1 activator; Co-beta-glucosidase; Glucosylceramidase activator; Sphingolipid activator protein 2; Saposin-D; Component C; Protein C

NCBI Accession #

NP_001035930.1;NP_001035931.1;NP_002769.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

58113

Recommended Dilutions

WB: 1:1000

Western blot analysis of SAP Antibody (Center E300) (Cat. 3102-17324) in Y79,A2058,CEM cell line lysates(35ug/lane). SAP (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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