Anti-SAR1B (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9Y6B6
Gene Id	51128
Gene Symbols	SAR1B
Protein Name / Synonyms	SAR1B (Center)
Clonality	Polyclonal
Preparation	This SAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human SAR1B.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	IHC-P, Western Blotting, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine, Hamster, Pig

Other Names

SAR1B; SARA2; SARB; GTP-binding protein SAR1b; GTP-binding protein B

NCBI Accession #

NP_001028675.1;NP_057187.1

Other Accession #

Q5HZY2; Q5PYH3; Q9CQC9; Q9QVY3; Q3T0T7; NP_057187.1; NP_001028675.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

22410

Recommended Dilutions

IHC: 1:50-100; WB: 1:1000; FC: 1:10-50

	SAR1B antibody (Center) (Cat# 102-10641) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SAR1B antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
	SAR1B Antibody (Center) (Cat# 102-10641) western blot analysis in MCF-7,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SAR1B antibody detected the SAR1B protein (arrow).
	SAR1B Antibody (Center) (Cat# 102-10641) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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