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Anti-SEC62 (N-term) Antibody
Catalog #: 102-11760
Rabbit Anti-Human SEC62 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q99442 |
| Gene Id | 7095 |
| Gene Symbols | SEC62 |
| Protein Name / Synonyms | SEC62 (N-term) |
| Clonality | Polyclonal |
| Preparation | This SEC62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEC62. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Specificity
Predicted Reactivity
Mouse
Other Names
SEC62; TLOC1; Translocation protein SEC62; Translocation protein 1
NCBI Accession #
NP_003253.1
Other Accession #
Q8BU14; NP_003253.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
45862
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | SEC62 Antibody (N-term) (Cat# 102-11760) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SEC62 antibody detected the SEC62 protein (arrow). |
 | SEC62 Antibody (N-term) (Cat# 102-11760)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SEC62 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.