RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

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770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-SENP1 (C-term) Antibody

Catalog #: 102-11505

Rabbit Anti-Human SENP1 (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q9P0U3
Gene Id
29843
Gene Symbols
SENP1
Protein Name / Synonyms
SENP1 (C-term)
ClonalityPolyclonal
PreparationThis SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-590 amino acids from the C-terminal region of human SENP1.
Concentration (lot specific)
1.930 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.

Specificity

Predicted Reactivity
Mouse
Other Names
SENP1; Sentrin-specific protease 1; Sentrin/SUMO-specific protease SENP1
NCBI Accession #
NP_001254523.1;NP_001254524.1
Other Accession #
P59110

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
73481
Recommended Dilutions
WB: 1:1000
Western blot analysis of hSENP1-K578 (Cat# 102-11505) in HL-60, Hela cell line lysates (35ug/lane). SENP1 (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.