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Anti-SEPSECS (C-term) Antibody

Catalog #: 102-13820

Rabbit Anti-Human SEPSECS (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q9HD40
Gene Id
51091
Gene Symbols
SEPSECS
Protein Name / Synonyms
SEPSECS (C-term)
ClonalityPolyclonal
PreparationThis SEPSECS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-474 amino acids from the C-terminal region of human SEPSECS.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

The 21st amino acid, selenocysteine (sec), is distinct from other amino acids because it lacks its own tRNA synthetase and is the only amino acid synthesized on its cognate tRNA. Synthesis of sec begins with acylation of tRNA(sec) (TRSP; MIM 165060) by seryl-tRNA synthetase (SARS; MIM 607529) to give ser-tRNA(sec), which is subsequently phosphorylated by O-phosphoseryl-tRNA kinase (PSTK; MIM 611310) to give O-phosphoseryl-tRNA(sec). SEPSECS catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor (Palioura et al., 2009 [PubMed 19608919]).

Specificity

Other Names
SEPSECS; TRNP48; O-phosphoseryl-tRNA(Sec) selenium transferase; Liver-pancreas antigen; SLA-p35; SLA/LP autoantigen; Selenocysteine synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep-tRNA:Sec-tRNA synthase; Soluble liver antigen; UGA suppressor tRNA-associated protein; tRNA(Ser/Sec)-associated antigenic protein
NCBI Accession #
NP_058651.3
Other Accession #
NP_058651.3

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
55726
Recommended Dilutions
WB: 1:1000
SEPSECS Antibody (C-term) (Cat# 102-13820) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SEPSECS Antibody detected the SEPSECS protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.