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Anti-SEPT2 (C-term) Antibody
Catalog #: 102-13129
Rabbit Anti-Human SEPT2 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15019 |
| Gene Id | 4735 |
| Gene Symbols | SEPT2 |
| Protein Name / Synonyms | SEPT2 (C-term) |
| Clonality | Polyclonal |
| Preparation | This SEPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human SEPT2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine
Other Names
SEPT2; DIFF6; KIAA0158; NEDD5; Septin-2; Neural precursor cell expressed developmentally down-regulated protein 5
NCBI Accession #
NP_001008491.1;NP_001008492.1;NP_004395.1;NP_006146.1
Other Accession #
Q91Y81; P42208; Q2NKY7; NP_001008492.1; NP_001008491.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
41487
Recommended Dilutions
WB: 1:1000
 | SEPT2 Antibody (C-term) (Cat# 102-13129) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SEPT2 antibody detected the SEPT2 protein (arrow). |
 | Western blot analysis of SEPT2 (arrow) using rabbit polyclonal SEPT2 Antibody (C-term) (Cat# 102-13129). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SEPT2 gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.