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Anti-SF3B1 (N-term) Antibody
Catalog #: 102-12140
Rabbit Anti-Human SF3B1 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O75533 |
| Gene Id | 23451 |
| Gene Symbols | SF3B1 |
| Protein Name / Synonyms | SF3B1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This SF3B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the N-terminal region of human SF3B1. |
| Concentration (lot specific) | 0.370 mg/ml |
| Recommended Applications | IHC-P, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Specificity
Predicted Reactivity
Mouse, Xenopus
Other Names
SF3B1; SAP155; Splicing factor 3B subunit 1; Pre-mRNA-splicing factor SF3b 155 kDa subunit; Spliceosome-associated protein 155
NCBI Accession #
NP_036565.2
Other Accession #
O57683; Q99NB9; NP_036565.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
145830
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | SF3B1 Antibody (N-term) (Cat# 102-12140) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SF3B1 antibody detected the SF3B1 protein (arrow). |
 | SF3B1 Antibody (N-term) (102-12140)immunohistochemistry analysis in formalin fixed and paraffin embedded human esophagus carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SF3B1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.