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Anti-SF3B3 (C-term) Antibody
Catalog #: 102-11693
Rabbit Anti-Human SF3B3 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15393 |
| Gene Id | 23450 |
| Gene Symbols | SF3B3 |
| Protein Name / Synonyms | SF3B3 (C-term) |
| Clonality | Polyclonal |
| Preparation | This SF3B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1046-1074 amino acids from the C-terminal region of human SF3B3. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
Specificity
Predicted Reactivity
Mouse, Bovine
Other Names
SF3B3; KIAA0017; SAP130; Splicing factor 3B subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; STAF130; Spliceosome-associated protein 130
NCBI Accession #
NP_036558.3
Other Accession #
Q921M3; A0JN52; NP_036558.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
135577
Recommended Dilutions
WB: 1:1000
 | SF3B3 Antibody (C-term) (Cat# 102-11693) western blot analysis in MDA-MB453,Jurkat cell line lysates (35ug/lane).This demonstrates the SF3B3 antibody detected the SF3B3 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.