Anti-SKP1 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P63208
Gene Id	6500
Gene Symbols	SKP1
Protein Name / Synonyms	SKP1 (Center)
Clonality	Polyclonal
Preparation	This SKP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the Central region of human SKP1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine, Chicken, Monkey, Xenopus

Other Names

SKP1; EMC19; OCP2; SKP1A; TCEB1L; S-phase kinase-associated protein 1; Cyclin-A/CDK2-associated protein p19; Organ of Corti protein 2; Organ of Corti protein II; RNA polymerase II elongation factor-like protein; SIII; Transcription elongation factor B; p19A; p19skp1

NCBI Accession #

NP_008861.2;NP_733779.1

Other Accession #

Q71U00; Q6PEC4; Q9WTX5; Q4R5B9; Q5ZKF5; Q3ZCF3

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

18658

Recommended Dilutions

WB: 1:1000

Western blot analysis of anti-SKP1A Pab (Cat# 102-14257) in CEM cell line lysate (35ug/lane). SKP1A(arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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