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Anti-SMC1A (N-term) Antibody
Catalog #: 102-12050
Rabbit Anti-Human SMC1A (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q14683 |
| Gene Id | 8243 |
| Gene Symbols | SMC1A |
| Protein Name / Synonyms | SMC1A (N-term) |
| Clonality | Polyclonal |
| Preparation | This SMC1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the N-terminal region of human SMC1A. |
| Concentration (lot specific) | 0.430 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq].
Specificity
Predicted Reactivity
Mouse, Bovine
Other Names
SMC1A; DXS423E; KIAA0178; SB1.8; SMC1; SMC1L1; Structural maintenance of chromosomes protein 1A; Sb1.8
NCBI Accession #
NP_006297.2
Other Accession #
Q9CU62; O97593; NP_006297.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
143233
Recommended Dilutions
WB: 1:1000
 | SMC1A Antibody (N-term) (Cat# 102-12050) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SMC1A antibody detected the SMC1A protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.