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Anti-SOX2 Antibody, Sodium Azide Free
Catalog #: 188-11149-SAF
Mouse anti-Human SOX2 Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Specificity | Other species not tested. |
| Host Species | Mouse |
| Accession Number | P48431 |
| Gene Id | 6657 |
| Gene Symbols | SOX2 |
| Protein Name / Synonyms | Transcription factor SOX-2 |
| Immunogen | Amino acids 176-305 of the human protein were used as the immunogen for the SOX2 antibody. |
| Isotype | Kappa, IgG2b |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | ELISA: 2-4ug/ml, order BSA-free formulation for coating Flow Cytometry: 0.5-1ug/million cells in 0.1ml Immunofluorescence: 1-2ug/ml Western blot: 0.5-1ug/ml Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT |
| Domain / Region / Terminus | Cytoplasmic, nuclear |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.
Storage
Store the SOX2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.