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Anti-SPAK (STK39) (C-term) Antibody

Catalog #: 102-12505

Rabbit Anti-Human SPAK (STK39) (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q9UEW8
Gene Id
27347
Gene Symbols
STK39
Protein Name / Synonyms
SPAK (STK39) (C-term)
ClonalityPolyclonal
PreparationThis SPAK (STK39) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SPAK (STK39).
Concentration (lot specific)
2.0 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Research AreaInflammation
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

STK39 is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.

Specificity

Predicted Reactivity
Rat
Other Names
STK39; SPAK; STE20/SPS1-related proline-alanine-rich protein kinase; DCHT; Serine/threonine-protein kinase 39
NCBI Accession #
NP_037365.2
Other Accession #
O88506

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
59474
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
STK39 Antibody (C-term) (Cat# 102-12505) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the STK39 antibody detected the STK39 protein (arrow).
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with STK39 antibody (C-term)(Cat# 102-12505), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.