Anti-SPRR1B (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P22528
Gene Id	6699
Gene Symbols	SPRR1B
Protein Name / Synonyms	SPRR1B (C-term)
Clonality	Polyclonal
Preparation	This SPRR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-89 amino acids from the C-terminal region of human SPRR1B.
Concentration (lot specific)	0.496 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

SPRR1B is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.

Specificity

Other Names

SPRR1B; Cornifin-B; 14.9 kDa pancornulin; Small proline-rich protein IB

NCBI Accession #

NP_003116.2

Other Accession #

P35321

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

9888

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	Western blot analysis of SPRR1B Antibody (C-term) (Cat# 102-18125) in MDA-MB231, MDA-MB435 cell line lysates (35ug/lane). SPRR1B (arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human breast carcinoma reacted with SPRR1B Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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