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Anti-SSX4 (Center) Antibody
Catalog #: 102-11914
Rabbit Anti-Human SSX4 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O60224 |
| Gene Id | 6759 |
| Gene Symbols | SSX4 |
| Protein Name / Synonyms | SSX4 (Center) |
| Clonality | Polyclonal |
| Preparation | This SSX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human SSX4. |
| Concentration (lot specific) | 0.310 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
Specificity
Other Names
SSX4; SSX4A; Protein SSX4; Cancer/testis antigen 5.4
NCBI Accession #
NP_001030004.1;NP_001035702.1;NP_005627.1;NP_783856.1
Other Accession #
NP_783856.1; NP_005627.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
21858
Recommended Dilutions
WB: 1:1000
 | SSX4 Antibody (Center) (Cat# 102-11914) western blot analysis in CEM,K562,NCI-H292,MDA-MB453,A549 cell line lysates (35ug/lane).This demonstrates the SSX4 antibody detected the SSX4 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.