Rabbit Anti-STK38 (C-term) Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15208 |
| Gene Id | 11329 |
| Gene Symbols | STK38 |
| Protein Name / Synonyms | Serine/threonine-protein kinase 38, NDR1 protein kinase, Nuclear Dbf2-related kinase 1, STK38 {ECO:0000312|EMBL:AAH120851} |
| Clonality | Polyclonal |
| Clone | RB9191 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Stk38,also known as NUCLEAR DBF2-RELATED PROTEIN, contains 1 protein kinase domain that interacts with mob1 and mob2.The homodimeric s100b binds to two molecules of stk38. It is ubiquitously expressed with highest levels observed in peripheral blood leukocytes. Stk38 activated by binding of s100b which releases autoinhibitory n-lobe interactions, enabling atp to bind and the autophosphorylation of ser-281. thr-444 then undergoes calcium- dependent phosphorylation by an upstream kinase. Interactions between phosphorylated thr-444 and the n-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of mob1/mobkl1a and mob2/hcca2 to the n-terminal of stk38.
Other Information
NCBI Accession #
NP_009202.1
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
54190
Antigen Source
Human
Images
WB (1:1000)
The anti-STK38 Pab (Cat. #102-27156) is used in Western blot to detect STK38 in SK-Br-3 (left) and Jurkat (right) cell line lysates.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.