RayBiotech

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Anti-STXBP2 Antibody

Catalog #: 144-07735

STXBP2 Polyclonal Antibody

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse, Rat
Host SpeciesRabbit
Accession Number
Q15833
Gene Id
6813
Gene Symbols
STXBP2
Protein Name / Synonyms
STXBP2, FHL5, Hunc18b, MUNC18-2, UNC18-2, UNC18B, pp10122, syntaxin-binding protein 2
ClonalityPolyclonal
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting, IHC
Shipping TypeBlue ice
Storage-20°C

Description

Background

This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Dilutions

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Format

Calculated MW
66kDa/67kDa
Observed MW
66kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human STXBP2 (NP_001120868.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using STXBP2 antibody (144-07735) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
Western blot - STXBP2 antibody (144-07735)

Immunohistochemistry of paraffin-embedded human prostate using STXBP2 antibody (144-07735) at dilution of 1:100 (40x lens).
Immunohistochemistry - STXBP2 antibody (144-07735)

Immunohistochemistry of paraffin-embedded mouse stomach using STXBP2 antibody (144-07735) at dilution of 1:100 (40x lens).
Immunohistochemistry - STXBP2 antibody (144-07735)

Expiration:
12 months from the date of shipment when stored properly.