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Anti-SUMO4 Antibody
Catalog #: 144-03100
SUMO4 Polyclonal Antibody
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q6EEV6 |
| Gene Id | 387082 |
| Gene Symbols | SUMO4 |
| Protein Name / Synonyms | SUMO4, IDDM5, SMT3H4, SUMO-4, dJ281H8.4, small ubiquitin-like modifier 4 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.
Dilutions
WB 1:1000 - 1:2000
IHC 1:100 - 1:300
IHC 1:100 - 1:300
Format
Calculated MW
10kDa
Observed MW
18kDa
Immunogen
A synthetic peptide of human SUMO4
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of various cell lines, using SUMO4 antibody (144-03100) at 1:800 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded human kidney cancer using SUMO4 Antibody (144-03100) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human appendicitis using SUMO4 Antibody (144-03100) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human breast cancer using SUMO4 Antibody (144-03100) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human kidney cancer using SUMO4 Antibody (144-03100) at dilution of 1:100 (40x lens).
Expiration:
12 months from the date of shipment when stored properly.