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Anti-SUV39H1 Antibody
Catalog #: 144-65687
SUV39H1 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | O43463 |
| Gene Id | 6839 |
| Gene Symbols | SUV39H1 |
| Protein Name / Synonyms | SUV39H1, H3-K9-HMTase 1, KMT1A, MG44, SUV39H, H3-K9-HMTase1, suppressor of variegation 3-9 homolog 1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC, IF, ChIP |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants.
Dilutions
WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200; ChIP 1:20 - 1:100
Format
Calculated MW
47kDa/49kDa
Observed MW
48kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SUV39H1 (NP_003164.1).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.