Anti-SUV4-20H2 (Center) Antibody

Product Description

Specifications

Size	200 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q86Y97\|P0C2N6\|Q6Q783
Gene Id	84787
Gene Symbols	KMT5C
Protein Name / Synonyms	Histone-lysine N-methyltransferase SUV420H2, Lysine N-methyltransferase 5C, Suppressor of variegation 4-20 homolog 2, Su(var)4-20 homolog 2, Suv4-20h2, SUV420H2, KMT5C
Clonality	Polyclonal
Clone	RB19392
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).

Other Information

NCBI Accession #

NP_116090.2

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Calculated Molecular Weight (Da)

52113

Antigen Source

Human

Images

WB (1:1000)

Western blot analysis of SUV4-20H2 antibody (Center) (Cat.# 102-27027) in mouse stomach tissue lysates (35ug/lane). SUV4-20H2 (arrow) was detected using the purified Pab.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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