Rabbit Anti-SWAP70 (Center) Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9UH65|Q6A028|P0C1G6 |
| Gene Id | 23075 |
| Gene Symbols | SWAP70 |
| Protein Name / Synonyms | Switch-associated protein 70, SWAP-70, SWAP70, KIAA0640 |
| Clonality | Polyclonal |
| Clone | RB12346 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
SWAP70 is a phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. This protein regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Other Information
NCBI Accession #
NP_055870.2
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
68998
Antigen Source
Human
Images
WB (1:1000)
Western blot analysis of SWAP70 (arrow) using rabbit polyclonal SWAP70 Antibody (Center) (Cat# 102-21861). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SWAP70 gene (Lane 2) (Origene Technologies).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.