Anti-TAS2R38 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Rat
Host Species	Rabbit
Accession Number	P59533
Gene Id	5726
Gene Symbols	TAS2R38
Protein Name / Synonyms	TAS2R38, PTC, T2R38, T2R61, taste 2 receptor member 38
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW

37kDa

Observed MW

38kDa

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 150-250 of human TAS2R38 (NP_789787.4).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of rat thymus, using TAS2R38 antibody (144-60908) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90.
Western blot - TAS2R38 antibody (144-60908)

Expiration:

12 months from the date of shipment when stored properly.

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