The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).

WB 1:500 - 1:2000

Recombinant fusion protein containing a sequence corresponding to amino acids 28-346 of human TFB1M (NP_057104.2).

Unmodified

Store at -20°. Avoid freeze / thaw cycles.