Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

WB 1:500 - 1:2000

Recombinant fusion protein containing a sequence corresponding to amino acids 24-129 of human TFF2 (NP_005414.1).

Unmodified

Store at -20°. Avoid freeze / thaw cycles.