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Anti-TGM2 Antibody
Catalog #: 144-00981
TGM2 Polyclonal Antibody
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P21980 |
| Gene Id | 7052 |
| Gene Symbols | TGM2 |
| Protein Name / Synonyms | TGM2, TG(C), TGC, transglutaminase 2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Research Area | Angiogenesis, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Dilutions
WB 1:500 - 1:2000
IHC 1:100 - 1:200
IHC 1:100 - 1:200
Format
Calculated MW
38kDa/61kDa/77kDa
Observed MW
90kDa
Immunogen
Recombinant protein of human TGM2
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of various cell lines, using TGM2 antibody (144-00981) at 1:300 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded mouse brain using TGM2 antibody (144-00981) (40x lens).
Immunohistochemistry of paraffin-embedded human lung cancer using TGM2 antibody (144-00981) (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using TGM2 antibody (144-00981) (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using TGM2 antibody (144-00981) (40x lens).
Expiration:
12 months from the date of shipment when stored properly.